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KMID : 0861220120140010036
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Journal of the Korean Society Clinical Neurophysiology
2012 Volume.14 No. 1 p.36 ~ p.40
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Nephrogenic Systemic Fibrosis with Myopathy
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Heo Deok-Hyun
Jang Il-Mi
Roh Hak-Jae
Ahn Moo-Young
Jin So-Young
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Abstract
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Nephrogenic systemic fibrosis (NSF) is a systemic disease that affects the skin and other tissues in patients with renal insufficiency and exposure to gadolinium-containing contrast. A 55-year-old woman with end-stage renal disease on hemodialysis was consulted for progressive general weakness. After she had undergone multiple MRIs with gadolinium-containing contrast media, muscle weakness and skin lesions were developed. Her skin and muscle biopsy specimens showed CD34+ fibroblast entrapping collagen bundles. There are few reports of NSF with myopathy.
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KEYWORD
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Nephrogenic systemic fibrosis, Fibroblast, Myopathy
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